Posts Tagged ‘ADHD and dopamine’

The Washington Post (9/22, Ellison) reports that, according to a study published Sept. 9 in the Journal of the American Medical Association, there may be “a striking difference in the brain’s motivational machinery in people with” attention-deficit hyperactivity disorder (AD/HD) symptoms. The study included “a group of healthy subjects” and “53 adults with AD/HD.” Researchers compared “detailed images of participants’ brains with positron emission tomography, or PET, scans after injecting them with a radioactive chemical that binds to dopamine receptors and transporters.” They found that “in people with AD/HD, the receptors and transporters aradhde significantly less abundant in mid-brain structures composing the so-called reward pathway, which is involved in associating stimuli with pleasurable expectations.” Researchers “speculated that people with AD/HD may even have a net deficit of dopamine.”


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Dopamine HealthDay (9/8, Dotinga) reported that, according to a study published Sept. 9 in the Journal of the American Medical Association, the “the trouble concentrating that affects people with attention-deficit hyperactivity disorder (AD/HD) might be related to motivation.” Specifically, “the motivational problems seen with” AD/HD “appear to stem from a reduction in” the neurotransmitter dopamine. For the study, researchers from the US National Institute on Drug Abuse and the Brookhaven National Laboratory recruited “53 adults with AD/HD” who “underwent positron emission tomography (PET) scans for dopamine markers.” Next, the team “compared the results with PET scans of 44 adults without the condition.” In participants with AD/HD, the investigators found “disruptions in the two dopamine pathways associated with reward and motivation.”   WebMD (9/8, Warner) pointed out that “the results offer new insight into AD/HD, as well as help explain why people with AD/HD may be more likely to abuse drugs or become obese.” Lead study author Nora D. Volkow, MD, stated, “Our results also support the continued use of stimulant medications — the most common pharmacological treatment for AD/HD — which have been shown to increase attention to cognitive tasks by elevating brain dopamine.”   CBC News (9/9), BBC News (9/8), the UK’s Daily Mail (9/9, Hope), and the UK’s Telegraph (9/8, Smith) also covered the story.

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