Posts Tagged ‘Alzheimer’s and APOE in CSF’

alzHealthDay (6/24, Preidt) reported that, according to a study published in the July issue of The Lancet Neurology, “biomarkers for Alzheimer’s disease can be detected in the cerebrospinal fluid in the very early stages of the disease.” For the study, researchers from Sweden’s University of Gothenburg “analyzed cerebrospinal fluid (CSF) samples from 168 patients and found the typical pattern of biomarkers known as the ‘CSF AD profile’ present in patients with mild memory problems, which is earlier than the illness could be detected by current tests.” In fact, “patients who had the typical changes in biomarker profile of the cerebrospinal fluid had a risk of deterioration that was 27 times higher than the control group,” the investigators found. In addition, the authors “found a relationship between the CFS AD profile and other typical signs of Alzheimer’s, including the presence of the gene APOE e4 and deterioration of the area of the brain that controls memory.”

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