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Posts Tagged ‘Archives of General Psychiatry’

WebMD (2/1, DeNoon http://tinyurl.com/fishy-psychosis) reported that twelve weeks of fish oil pills made teens at high risk of psychosis much less likely to become psychotic for at least one year.   A year after entering the study, 11 of the 40 teens treated only with placebo pills developed a psychotic disorder.  This happened to only two of 41 teens who began the year with 12 weeks of fish oil capsules rich in omega-3 fatty acids.    “The finding that treatment with a natural substance may prevent or at least delay the onset of psychotic disorder gives hope that there may be alternatives to antipsychotics for the prodromal phase”, Amminger and colleagues suggest.    People with schizophrenia tend to have low levels of omega-3 fatty acids, suggesting that the mental illness could be linked to a defect in the ability to process fatty acids.  There’s also evidence that fatty acids interact with chemical signaling in the brain and that omega-3 fatty acids protect brain cells from oxidative stress.  The study appears in the February issue of Archives of General Psychiatry.

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According to a study in the Archives of General Psychiatry (http://tinyurl.com/lead-and-psychiatry), in young adults with low levels of lead exposure, higher blood lead levels were associated with increased odds of major depression and panic disorders. Exposure to lead at levels generally considered safe could result in adverse mental health outcomes.  The mean blood lead level was 1.61 µg/dL.  Increasing blood lead levels were associated with higher odds of major depression and panic disorder but not generalized anxiety disorder.  Persons with blood lead levels in the highest quintile had 2.3 times the odds of major depressive disorder  and 4.9 times the odds of panic disorder as those in the lowest quintile.  Cigarette smoking was associated with higher blood lead levels and outcome, but models that excluded current smokers also resulted in significantly increased odds of major depression and panic disorder with higher blood lead quintiles.

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