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Posts Tagged ‘caffeine and alzheimers’

BBC News (7/5) reported that, according to a mouse study published in the July 5 online edition of the Journal of Alzheimer’s Disease, “drinking five cups of coffee a day could reverse memory problems seen in Alzheimer’s disease.” For the study, researchers from the University of Florida studied “55 mialzce…bred to develop symptoms of Alzheimer’s disease (AD)” and found that “caffeine hampered the production of the” beta-amyloid “protein plaques which are the hallmark of” AD. The team used “behavioral tests to confirm the mice were exhibiting signs of memory impairment when they were aged 18 to 19 months, the equivalent to humans being about 70,” then “gave half the mice caffeine in their drinking water. The rest were given plain water.” The animals received “the equivalent of five 8 oz. (227 grams) cups of coffee a day — about 500 milligrams of caffeine.”
        The UK’s Telegraph (7/5) explained that “at the end of the two-month study, the caffeine-drinking mice performed far better on tests of memory and thinking than mice given only water.” In fact, “their memories were as sharp as those of healthy older mice without dementia.” For humans, the “equivalent dose for their body weight would be consuming 500 milligrams of caffeine a day, equivalent to five cups of ordinary coffee,” which is “the same amount of caffeine can be obtained by drinking two cups of strong coffee, 14 cups of tea, or 20 cola drinks.”
        HealthDay (7/5, McKeever) pointed out that, according to the study’s authors, “consuming 500 milligrams of caffeine a day would not cause ill effects for most people,” but “people with high blood pressure or who are pregnant need to limit their caffeine intake.” Notably, the study authors “also found that caffeine did not improve the memory of normal mice as it did for the Alzheimer’s mice.” They concluded, “This suggests that caffeine will not increase memory performance above normal levels. Rather, it appears to benefit those destined to develop Alzheimer’s disease.”

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