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Posts Tagged ‘cocaine addction’

The New York Times http://tinyurl.com/cocaine-vaccine-NYT (10/6, A18, Rabin) reports, “Scientists say they have developed a cocaine vaccine that can prevent addicts from getting high by blocking the drug’sCocaine effect on the brain, though it does not blunt cravings for the drug,” according to a study  http://tinyurl.com/cocaine-vaccine-gen-psych
published in the Archives of General Psychiatry. Researchers reported that although “the vaccine had only limited success, it created enough of an immune response in some subjects that many of them cut their drug use by half.” The Times notes that the “trial’s success is significant, because some of the same principles are being used by other scientists in trying to create an anti-nicotine vaccine, which could have even broader appeal.  ” The AP (10/6) adds that the results from the study “come just days after” the National Institute on Drug Abuse (NIDA) “announced plans for the first late-stage study of an experimental nicotine vaccine designed to help people quit smoking,” which “has been fast-tracked by the Food and Drug Administration, and the research will be paid for with federal stimulus money.”  Bloomberg News http://tinyurl.com/cocaine-vaccine-bloomberg (10/6, Lopatto) also reports that the 12-week cocaine vaccine trial “injected patients five times with either a placebo vaccine or a cholera vaccine with cocaine hooked on to it, to provoke an immune response.”  “Thirty-eight percent of the subjects receiving the vaccine produced antibody levels strong enough to prevent cocaine highs despite many dosages of the drug, and another 37 percent had antibody levels strong enough to prevent highs to one or two doses. The rest had little or no response,” according to the Houston Chronicle
(10/6, Ackerman).   The Chicago Tribune (10/6, Roan, Kaplan) notes, “Vaccines to help people recover from addictions to such substances as nicotine, cocaine, heroin, and methamphetamines appear scientifically achievable after doctors reported Monday” the results of their work on the cocaine vaccine. The Los Angeles Times(10/5, Roan) “Booster Shots” blog pointed out that about “300 cocaine-dependent individuals will be enrolled in a study beginning in January to further test the vaccine.”  WebMD (10/5, Warner) and Healthday (10/5, Gardner) also covered the story.

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