Posts Tagged ‘ECT and antidepressants’

ectMedscape (7/10, Kelly) reported that, according to a study published in the July issue of Archives of General Psychiatry, “combining antidepressant” medications “with electroconvulsive therapy (ECT) does a better job of reducing symptoms of severe depression and causes less memory loss than using ECT alone.” For the study, researchers from Columbia University “randomized 319 patients who had major depression to receive either a placebo or one of two antidepressants: nortriptyline or venlafaxine, starting the afternoon following the first ECT treatment.” Electroconvulsive therapy “was given three times per week.” Meanwhile “a battery of cognitive tests was administered before ECT and one to four days following all ECT.” The team found that “using either antidepressant during ECT improved depression more than ECT alone and that adding nortriptyline to ECT increased remission rates by about 15 percent.” In addition, “patients who received nortriptyline during ECT had fewer memory problems than those in the venlafaxine group.”

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